Tablets

Leril-M

Description:

Levocetirizine, the R-enantiomer of cetirizine, is a potent and selective antagonist of peripheral H1-receptors.Montelukast sodium is an orally active compound that binds with high affinity and selectivity to the CysLT type-1 (CysLT1) receptor. Montelukast inhibits physiologic actions of LTD4 at the CysLT1 receptor without any agonist activity. It therefore acts as a leukotriene receptor antagonist.

Composition

Levocetrizine 5 mg + Montelukast 10 mg

Description

Levocetirizine, the R-enantiomer of cetirizine, is a potent and selective antagonist of peripheral H1-receptors.Montelukast sodium is an orally active compound that binds with high affinity and selectivity to the CysLT type-1 (CysLT1) receptor. Montelukast inhibits physiologic actions of LTD4 at the CysLT1 receptor without any agonist activity. It therefore acts as a leukotriene receptor antagonist

 

Indications

Seasonal allergic rhinitis perennial allergic rhinitis, ocular symptom (redness, lacrimation and itching) chronic idiopathic urticaria, urticaria dermographism, atopic aczema and contract dermatitis also in acute allergic reactions due to drugs foods and insect bites.

contraindications

In severe renal impairment.

Special Precautions

Patients intending to drive/operate machinery or ingage in potentially hazardons activities should be warned not to take more than the recommended dose. Concurrent use with alcohol or other CNS depressant may cause reduction in alertness and impairment of performance. To be used cautionsly in pregnancy lactation and children below 6 years of age. 

Side Effects

Although well tolerated some effects are headache, somnolence, dry mouth, mild drowsiness and G.I. disturbances. 

Drug Interactions

Rate of absorption is reduced with food. Alcohol and CNS depressants may potentiate CNS side effects in sensitive patients.