Tablets

Composition

Azithromycin 250 mg
Azithromycin 500 mg

Description

Azithromycin is an azalide antibiotic a subclass of the macrolides. It retains the spectrum of activity of erythromycin against Gram positive and Gram negative and atypical micro organisms. It has greater acid stability than erythromycin and its gastrointestinal tolerance is better than that of erythromycin. It acts by interfering with microbial protein synthesis by binding to the 50s  ribosomal subunit.

 

Indications

Upper and lower respiratory tract infections, skin and soft tissues infections, Urogenital infections.

Contraindications

Hypersensitivity to Azithromycin or other macrolides.

Special Precautions

Pseudomembranous colitis, impaired liver function, impaired renal function, antacids, containing aluminium and magnesium, children.
Paediatrics: Reduced dose necessary. Not recommended in children below the age of 6 months.
Pregnancy: Use with caution
Lactation: Use with caution
Elderly: No special problem

 

Side Effects

Nausea, vomiting, abdominal pain, diarrhea, dyspepsia, flatulence, dizziness, headache, vertigo.

 

Drug Interactions

Absorption reduced by food. Antacids reduce rate of absorption. Increases absorption of Digoxin and Cyclosporine.