It is analgesic and antipyretic in action, apart from its anti inflammatory action. Unlike other NSAID’s the chemical structure of Nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group. It is absorbed rapidly and completely after oral administration. It acts by inhibiting the release of tumour necrosis factor alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation.
Nimesulide 100mg + Serratiopeptidase 10mg
It is analgesic and antipyretic in action, apart from its anti inflammatory action. Unlike other NSAID’s the chemical structure of Nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group. It is absorbed rapidly and completely after oral administration. It acts by inhibiting the release of tumour necrosis factor alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation.
Rheumatoid arthritis, osteoarthritis, other degenerative joint disorder, musculoskeletal disorder, low back pain, dysmenorrhoea, gynecological conditions, thrombophlebitis dental pain and in ENT inflammations. In children: Fever and other sign and in RT inflammation.
Epigastric pain, hurt burn, nausea, diarrhea, vomiting skin rash pruritus dizziness somnolescence headache.
Displace methotrexate from its binding sites decrease the plasma level of theophylline oral bioavailability of frusemide may be reduced, displaced by the concomitant use of fenofibrate, salicylic acid, valproic acid.
Active peptic ulcer, elderly patients with moderate renal impairment, congestive heart failure or cirrhosis.
Hypersensitivity, active peptic ulcer disease, hepatic impairment.
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