Rabeprazole is a PPI that suppresses gastric acid secretion by inhibiting the gastric H+/K+ ATPase at the secretory surface of the gastric parietal cell.
Itopride increases acetylcholine (ACh) concentrations by inhibiting dopamine D2 receptors and acetylcholinesterase. Higher ACh increases GI peristalsis, increases the lower oesophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination. Rabeprazole Sodium / Itopride Hcl improves the patient's condition by performing the following functions:
Decreasing the amount of acid made by the stomach.
Accelerating the emptying of food from the stomach.
Rabeprazole Sodium 20mg + Itopride HCL 150mg
Rabeprazole is a PPI that suppresses gastric acid secretion by inhibiting the gastric H+/K+ ATPase at the secretory surface of the gastric parietal cell.
Itopride increases acetylcholine (ACh) concentrations by inhibiting dopamine D2 receptors and acetylcholinesterase. Higher ACh increases GI peristalsis, increases the lower oesophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination.
Rabeprazole Sodium / Itopride Hcl improves the patient's condition by performing the following functions:
Decreasing the amount of acid made by the stomach.
Accelerating the emptying of food from the stomach.
Stomach acid
Gastroesophageal reflux disease
Duodenal ulcers
Functional dyspepsia
Gastrointestinal conditions
Once or Twice Daily
Insomnia, Headache, Dizziness, Cough, Sore throat, Rhinitis, Diarrhoea. Vomiting, Nausea, Abdominal pain, Constipation, Flatulence, Pain, Asthenia, Sleeping disorders
Stomach pain, Chest pain, Gynaecomastia, Exhaustion, Increased salivation, Diarrhea, Galactorrhea
Rabeprazole increase elimination T1/2 of digoxin, decreases effects with aminoglutethimide, carbamazepine, phenytoin and rifampin and reduces absorption of ketoconazole and itraconazole.Anticholinergic agents reduces the action of itopride.
Avoid alcohol (may irritate gastric mucosa). Rabeprazole has delayed absorption but unaltered Cmax and AUC with high-fat meals.
10x10
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