Tablets

Composition

Diclofenac Potassium 50mg + Paracetamol 325mg

Description

Diclofenac Potassium: It is a non steroidal anti inflammatory, analgestic and antipyretic, drug. Diclofenac inhibits prostaglandin synthesis by interfering with the action by prostaglandin synthetase which explains its action. It is ideally suited for patients on sodium free diet, hypertensive patients, to treat painful inflammatory conditions of patients on diuretic therapy.

Paracetamol: (Acetaminophen) Paracetamol is a valuable central analgestic but weak peripheral anti inflammatory agent and exhibits good and prompt antipyretic action. It does not stimulate respiration, or after acid base balance and causes less gastric irritation and have no effect on cellular metabolism or clotting factors. It is not uricosuric.

 

Indications

Post operative and post traumatic inflammation muscular and skeletal pain and other co-existing conditions like spondylitis, Rheumatoid arthritis and Osteoarthritis.

Side-Effects

Nausea, rashes, leukopenia is rare.

Special Precautions

 Renal and hepatic impairment

Drug Interactions

Enhances oral anticoagulant activity. Absorption increased by metoclopramide. Absorption reduced b pethidine, propanthline. Alcohol (chronic use) potentiates hepatotoxicity by paracetamol.

Contraindications

Peptic ulcer, known hypersensitivity to the active substance, acetyl salicylic acid or other prostaglandin synthetase inhibiting drugs